SCHEMBL25964111

SCHEMBL25964111

CCCCC(=O)N(Cc1ccc(-c2ccccc2C(=N)N)cc1)[C@H](C(=O)OC)C(C)C

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 8/20 0.67
LTB4R2 Q9NPC1 14/20 0.59
ABCB11 O95342 1/20 0.54
GP6 Q9HCN6 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25964104 1.00 AGTR1 (0.67) AGTR1LTB4R2ABCB11GP6
SCHEMBL25964113 0.90 LTB4R2 (0.66) AGTR1LTB4R2ABCB11GP6
SCHEMBL21619427 0.89 AGTR1 (0.62) AGTR1LTB4R2ABCB11GP6
SCHEMBL17268552 0.86 LTB4R2 (0.51) AGTR1LTB4R2ABCB11GP6
SCHEMBL12715972 0.83 AGTR1 (0.67) AGTR1LTB4R2ABCB11GP6
SCHEMBL2032 0.82 AGTR1 (0.66) AGTR1LTB4R2ABCB11GP6
SCHEMBL2033 0.82 AGTR1 (0.66) AGTR1LTB4R2ABCB11GP6
SCHEMBL1808771 0.82 AGTR1 (0.66) AGTR1LTB4R2ABCB11GP6
SCHEMBL29561367 0.82 AGTR1 (0.66) AGTR1LTB4R2ABCB11GP6
SCHEMBL19342800 0.81 LTB4R2 (0.63) AGTR1LTB4R2ABCB11GP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023148748-A1 AN IMPROVED SAFE PROCESS FOR THE PREPARATION OF SARTAN DRUGS OF FORMULA I IOL CHEMICALS AND PHARMACEUTICALS LIMITED (IN) 2023-08-10 WO disclosed