Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25963054 | 0.87 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2LMNAADRB2 | |
| SCHEMBL26551992 | 0.85 | KMT2A (0.45) | MEN1KMT2ASMN1; SMN2LMNACHRNB2 | |
| SCHEMBL25963053 | 0.85 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2LMNACHRNB2 | |
| SCHEMBL12445443 | 0.84 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL25129535 | 0.84 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL23386933 | 0.84 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL27371560 | 0.84 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL25128825 | 0.84 | KMT2A (0.59) | MEN1KMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL27375087 | 0.84 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL20223534 | 0.84 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2LMNACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230256109-A1 | Trans-Cyclooctene Bioorthogonal Agents and Uses in Cancer and Immunotherapy | TAMBO, INC. | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230256109-A1 | Trans-Cyclooctene Bioorthogonal Agents and Uses in Cancer and Immunotherapy | ICOS, CD74, PBK | MEN1 862/4885KMT2A 3246/4885EPHX1 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.