Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20223534 | 0.86 | MEN1 (0.44) | KMT2AMEN1LMNASMN1; SMN2ACHE | |
| SCHEMBL25965105 | 0.85 | MEN1 (0.49) | KMT2AMEN1LMNASMN1; SMN2ACHE | |
| SCHEMBL20223529 | 0.84 | LMNA (0.43) | KMT2AMEN1LMNASMN1; SMN2ACHE | |
| SCHEMBL11141024 | 0.83 | ACHE (0.52) | KMT2AMEN1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL25963054 | 0.83 | MEN1 (0.46) | KMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL22691294 | 0.82 | LMNA (0.45) | KMT2AMEN1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL20149248 | 0.82 | L3MBTL1 (0.42) | KMT2AMEN1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL27357775 | 0.81 | ACHE (0.47) | KMT2AMEN1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL26460411 | 0.81 | ACHE (0.47) | KMT2AMEN1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL27357778 | 0.81 | ACHE (0.47) | KMT2AMEN1L3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330247-A1 | MUSCLE TARGETING COMPLEXES AND FORMULATIONS FOR TREATING MYOTONIC DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |
| US-20230330247-A1 | MUSCLE TARGETING COMPLEXES AND FORMULATIONS FOR TREATING MYOTONIC DYSTROPHY | DYNE THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330247-A1 | MUSCLE TARGETING COMPLEXES AND FORMULATIONS FOR TREATING MYOTONIC DYSTROPHY | MYOF, MUSK, DMPK | KMT2A 3427/4885MEN1 2987/4885L3MBTL1 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.