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SCHEMBL25965894

SCHEMBL25965894

c1ccc(-n2c3ccccc3c3c2ccc2c4ccccc4n(-c4cccc(-c5nc(-c6ccc7c(c6)oc6ccccc67)nc(-n6c7ccccc7c7ccccc76)n5)c4)c23)cc1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ LMNA P02545 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965873 1.00 KDM4E (0.35) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL26473051 0.96 HCRTR1 (0.31) —
SCHEMBL25964777 0.96 KDM4E (0.36) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25964754 0.96 KDM4E (0.36) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25010835 0.95 MMP12 (0.32) ATM
SCHEMBL20315831 0.95 MMP12 (0.32) ATM
SCHEMBL25965464 0.95 KDM4E (0.35) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25965453 0.95 KDM4E (0.35) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL19769905 0.95 KDM4E (0.34) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL24800909 0.95 KDM4E (0.35) KDM4EATML3MBTL1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed