Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | ESR1 | P03372 | 6/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.71 |
| ▸ | ATM | Q13315 | 3/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.71 |
| ▸ | SHBG | P04278 | 1/20 | 0.71 |
| ▸ | FYN | P06241 | 1/20 | 0.71 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.71 |
| ▸ | HTR2B | P41595 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300046 | 0.91 | LMNA (0.80) | LMNAMAPTKMT2AESR1SMN1; SMN2 | |
| SCHEMBL9404737 | 0.91 | MAPT (0.83) | LMNAMAPTKMT2AESR1SMN1; SMN2 | |
| SCHEMBL8155723 | 0.89 | MAPT (0.81) | LMNAMAPTKMT2AESR1SMN1; SMN2 | |
| SCHEMBL3868065 | 0.86 | MAPT (0.66) | LMNAMAPTKMT2AESR1SMN1; SMN2 | |
| SCHEMBL146888 | 0.85 | LMNA (0.82) | LMNAMAPTKMT2AESR1SMN1; SMN2 | |
| SCHEMBL3299315 | 0.85 | MAPT (0.81) | LMNAMAPTKMT2AESR1SMN1; SMN2 | |
| Estradiol Cypionate SCHEMBL7180612 | 0.85 | LMNA (0.74) | LMNAMAPTKMT2AESR1SMN1; SMN2 | |
| SCHEMBL8465006 | 0.85 | MAPT (0.79) | LMNAMAPTKMT2AESR1SMN1; SMN2 | |
| SCHEMBL9173174 | 0.85 | LMNA (0.66) | LMNAMAPTKMT2AESR1SMN1; SMN2 | |
| SCHEMBL24102647 | 0.85 | LMNA (0.81) | LMNAMAPTKMT2AESR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011143208-A1 | GLUCAGON SUPERFAMILY PEPTIDES EXHIBITING G PROTEIN-COUPLED RECEPTOR ACTIVITY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2011-11-17 | — | — | WO | disclosed |