⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801948 | 0.66 | — | — | |
| SCHEMBL13976324 | 0.66 | — | — | |
| SCHEMBL13811599 | 0.62 | — | — | |
| SCHEMBL27867560 | 0.62 | — | — | |
| SCHEMBL92802 | 0.57 | NOS1 (0.46) | — | |
| SCHEMBL11884517 | 0.54 | GLA (0.36) | — | |
| SCHEMBL14809378 | 0.54 | — | — | |
| SCHEMBL48367 | 0.54 | — | — | |
| SCHEMBL24066371 | 0.53 | MAPT (0.39) | — | |
| SCHEMBL14697635 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250087-A1 | SOLID FORMS OF APOL1 INHIBITOR AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED | 2023-08-10 | — | — | US | disclosed |