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SCHEMBL25965683

SCHEMBL25965683

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc(-n5c6ccccc6c6ccc7c(c65)-c5ccccc5C75c6ccccc6-c6ccccc65)c4)n3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DUSP3 P51452 1/20 0.32
▸ PDE10A Q9Y233 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25966498 0.99 KDM4E (0.33) DUSP3PDE10AKDM4EATML3MBTL1
SCHEMBL25965924 0.98 PDE10A (0.33) DUSP3PDE10A
SCHEMBL25121562 0.98 PDE10A (0.34) DUSP3PDE10AKDM4EATML3MBTL1
SCHEMBL15832136 0.98 DUSP3 (0.33) DUSP3PDE10AKDM4EATML3MBTL1
SCHEMBL25966499 0.97 KDM4E (0.34) DUSP3PDE10AKDM4EATML3MBTL1
SCHEMBL25965958 0.97 DUSP3 (0.31) DUSP3PDE10A
SCHEMBL25965745 0.97 PDE10A (0.33) DUSP3PDE10AKDM4EATML3MBTL1
SCHEMBL25966400 0.97 KDM4E (0.34) DUSP3PDE10AKDM4EATML3MBTL1
SCHEMBL25966401 0.96 KDM4E (0.35) DUSP3KDM4EATML3MBTL1
SCHEMBL15832284 0.96 DUSP3 (0.32) DUSP3PDE10AKDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed