Sugi Predict

Sugi Predict / Compounds / SCHEMBL25965745

SCHEMBL25965745

SCHEMBL25965745

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4cccc(-n5c6ccccc6c6ccc7c(c65)-c5ccccc5C75c6ccccc6-c6ccccc65)c4)n3)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PDE10A Q9Y233 1/20 0.33
▸ DUSP3 P51452 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.30
▸ ATM Q13315 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965924 0.99 PDE10A (0.33) PDE10ADUSP3
SCHEMBL15832284 0.99 DUSP3 (0.32) PDE10ADUSP3KDM4EATML3MBTL1
SCHEMBL25121562 0.97 PDE10A (0.34) PDE10ADUSP3KDM4EATML3MBTL1
SCHEMBL25965683 0.97 DUSP3 (0.32) PDE10ADUSP3KDM4EATML3MBTL1
SCHEMBL15832136 0.97 DUSP3 (0.33) PDE10ADUSP3KDM4EATML3MBTL1
SCHEMBL25966498 0.96 KDM4E (0.33) PDE10ADUSP3KDM4EATML3MBTL1
SCHEMBL25966400 0.96 KDM4E (0.34) PDE10ADUSP3KDM4EATML3MBTL1
SCHEMBL15840275 0.95 KDM4E (0.35) PDE10ADUSP3KDM4EATML3MBTL1
SCHEMBL17379731 0.95 PDE10A (0.31) PDE10A
SCHEMBL25965958 0.94 DUSP3 (0.31) PDE10ADUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed