SCHEMBL15832136

SCHEMBL15832136

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5ccc6c(c54)-c4ccccc4C64c5ccccc5-c5ccccc54)c3)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DUSP3 P51452 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
PDE10A Q9Y233 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25966400 0.99 KDM4E (0.34) DUSP3KDM4EATML3MBTL1MEN1
SCHEMBL25965683 0.98 DUSP3 (0.32) DUSP3KDM4EATML3MBTL1MEN1
SCHEMBL15832284 0.98 DUSP3 (0.32) DUSP3KDM4EATML3MBTL1MEN1
SCHEMBL15840275 0.98 KDM4E (0.35) DUSP3KDM4EATML3MBTL1MEN1
SCHEMBL25966498 0.97 KDM4E (0.33) DUSP3KDM4EATML3MBTL1PDE10A
SCHEMBL25965745 0.97 PDE10A (0.33) DUSP3KDM4EATML3MBTL1PDE10A
SCHEMBL25966315 0.97 DUSP3 (0.32) DUSP3KDM4EATML3MBTL1
SCHEMBL25965798 0.96 DUSP3 (0.31) DUSP3
SCHEMBL25966401 0.96 KDM4E (0.35) DUSP3KDM4EATML3MBTL1
SCHEMBL25965924 0.96 PDE10A (0.33) DUSP3PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230108986-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-04-06 US disclosed
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-05-20 US disclosed
US-10847727-B2 Compositions for electronic devices MERCK PATENT GMBH (DE) 2020-11-24 US disclosed
EP-3158597-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-23 EP disclosed
US-10629817-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2020-04-21 US disclosed
WO-2019192954-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-10-10 WO disclosed
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-06-27 US disclosed
US-10227528-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2019-03-12 US disclosed
US-20180212159-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180212159-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20160155959-A1 Organic Electroluminescent Device MERCK PATENT GMBH (DE) 2016-06-02 US disclosed
WO-2015192941-A1 COMPOSITIONS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-12-23 WO disclosed
WO-2015192939-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-12-23 WO disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150340621-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150340621-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
WO-2015000548-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-01-08 WO disclosed
WO-2014094964-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed
WO-2014094963-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10227528-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM DUSP3 3224/4885KDM4E 2105/4885ATM 2996/4885
US-10847727-B2 Compositions for electronic devices EFNA1, EPHA6, EPHB6 DUSP3 3227/4885KDM4E 2520/4885ATM 2646/4885
US-20180212159-A1 ORGANIC ELECTROLUMINESCENT ELEMENT EML4, EPCAM, L1CAM DUSP3 4580/4885KDM4E 2054/4885ATM 1658/4885
US-20190194219-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH SAME OR10J3, EML4, AOC2 DUSP3 4546/4885KDM4E 2872/4885ATM 2194/4885
US-10629817-B2 Materials for organic electroluminescent devices KCNB2, KCNB1, GJB2 DUSP3 4827/4885KDM4E 3816/4885ATM 3054/4885
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EML4, L1CAM DUSP3 3107/4885KDM4E 2176/4885ATM 3105/4885
US-20210147375-A1 MATERIALS FOR ELECTRONIC DEVICES PNMT, EFNA1, TES DUSP3 4367/4885KDM4E 1633/4885ATM 2836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.