SCHEMBL25965705

SCHEMBL25965705

Cc1ccc2ccccc2c1N(c1ccc(C(C)C)cc1)c1cc(C(C)C)c2ccc3c(N(c4ccc(C(C)C)cc4)c4c(C)ccc5ccccc45)cc(C(C)C)c4ccc1c2c43

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.33
CYP1A2 P05177 4/20 0.32
MAPT P10636 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ACHE P22303 1/20 0.32
SLC6A2 P23975 1/20 0.32
AHR P35869 1/20 0.32
CYP2A6 P11509 1/20 0.31
TSHR P16473 1/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
CYP2C19 P33261 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CRHR1 P34998 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21475617 0.89 CYP1A2 (0.30) CYP1A2CYP2A6
SCHEMBL24699792 0.83 CYP2A6 (0.33) CYP1A2CYP2A6
SCHEMBL21475599 0.81 CYP1A2 (0.31) CYP1A2CYP2A6
SCHEMBL21870395 0.80 ALDH1A1 (0.34) CYP1A2MAPTALDH1A1CYP3A4GAA
SCHEMBL13227440 0.80 ALDH1A1 (0.34) CYP1A2MAPTALDH1A1CYP3A4GAA
SCHEMBL10066489 0.80 AR (0.31)
SCHEMBL24699807 0.79 KDM1A (0.32)
SCHEMBL21473873 0.79 LMNA (0.32) CYP1A2ALDH1A1CYP2A6GAA
SCHEMBL24699027 0.78
SCHEMBL10354393 0.78 CNR1 (0.34) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed