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SCHEMBL25965964

SCHEMBL25965964

c1ccc(-c2ccc(-c3nc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5cc6c(cc54)-c4ccccc4C64c5ccccc5-c5ccccc54)n3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ ATM Q13315 1/20 0.31
▸ PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25121568 0.98 MEN1 (0.34) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL25121742 0.98 MEN1 (0.34) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL25966323 0.98 KDM4E (0.31) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL25121857 0.97 TSPO (0.33) PDK2
SCHEMBL25965970 0.95 MEN1 (0.31) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2603654 0.95 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2603494 0.95 MEN1 (0.33) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20199579 0.94 MEN1 (0.32) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL25965925 0.93 MEN1 (0.32) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24078465 0.93 MEN1 (0.34) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed