SCHEMBL2603494

SCHEMBL2603494

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc5c(cc43)-c3ccccc3C53c4ccccc4-c4ccccc43)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
MAPT P10636 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ATM Q13315 2/20 0.32
KDM4E B2RXH2 2/20 0.31
LMNA P02545 2/20 0.31
OPRK1 P41145 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
ABCG2 Q9UNQ0 2/20 0.30
ABCB1 P08183 1/20 0.30
POLB P06746 1/20 0.30
DUSP3 P51452 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2603654 1.00 MEN1 (0.33) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL20199579 0.99 MEN1 (0.32) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25121568 0.98 MEN1 (0.34) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25121742 0.98 MEN1 (0.34) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25966323 0.98 KDM4E (0.31) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25121858 0.95 ADORA3 (0.30) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL25965964 0.95 MEN1 (0.31) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL801925 0.95 MEN1 (0.33) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL2603568 0.95 MEN1 (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL2603571 0.94 L3MBTL1 (0.39) MEN1KMT2AMAPTALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 US disclosed
US-11730052-B2 Light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-15 US disclosed
US-20230108986-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-04-06 US disclosed
US-20210198567-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-07-01 US disclosed
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-04-11 US disclosed
US-10186665-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2019-01-22 US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 US disclosed
US-9882144-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-01-30 US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 US disclosed
US-20160028025-A1 LIGHT-EMITTING DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-28 US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 US disclosed
US-20150340623-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-11-26 US disclosed
US-9040172-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-05-26 US disclosed
US-9040172-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-05-26 US disclosed
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-04-26 US disclosed
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-04-26 US disclosed
WO-2011000455-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2011-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190109285-A1 ORGANIC ELECTROLUMINESCENT ELEMENT TCF4, TRPA1, EML4 MEN1 2279/4885KMT2A 1347/4885MAPT 1068/4885
US-11730052-B2 Light-emitting device GRK7, GRK1, CTNND1 MEN1 3144/4885KMT2A 3535/4885MAPT 1228/4885
US-20120097899-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, ICMT, NUDC MEN1 1890/4885KMT2A 3703/4885MAPT 1086/4885
US-10186665-B2 Organic electroluminescent element TCF4, TRPA1, EML4 MEN1 2279/4885KMT2A 1347/4885MAPT 1068/4885
US-20160197287-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AOC2, AZI2, RER1 MEN1 886/4885KMT2A 1282/4885MAPT 3937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.