SCHEMBL25965992

SCHEMBL25965992

c1ccc(-c2ccc(-c3nc(-c4ccc(-n5c6ccccc6c6c7c8ccccc8n(-c8ccccc8)c7ccc65)cc4)nc(-n4c5ccccc5c5ccccc54)n3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.49
ATM Q13315 2/20 0.49
KDM4E B2RXH2 1/20 0.49
HDAC4 P56524 1/20 0.38
AVPR1A P37288 1/20 0.37
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
RAB9A P51151 1/20 0.36
IL1R1 P14778 1/20 0.36
HTT P42858 2/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
MAPK1 P28482 1/20 0.35
PTGER4 P35408 1/20 0.34
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25966358 0.99 L3MBTL1 (0.50) L3MBTL1ATMKDM4EHDAC4AVPR1A
SCHEMBL17248190 0.97 L3MBTL1 (0.47) L3MBTL1ATMKDM4EHDAC4AVPR1A
SCHEMBL18124851 0.97 ATM (0.43) L3MBTL1ATMKDM4EHDAC4AVPR1A
SCHEMBL26053729 0.97 ATM (0.43) L3MBTL1ATMKDM4EHDAC4AVPR1A
SCHEMBL18708367 0.97 ATM (0.43) L3MBTL1ATMKDM4EHDAC4AVPR1A
SCHEMBL23805714 0.97 ATM (0.43) L3MBTL1ATMKDM4EHDAC4AVPR1A
SCHEMBL19769803 0.97 L3MBTL1 (0.47) L3MBTL1ATMKDM4EHDAC4AVPR1A
SCHEMBL20315781 0.97 ATM (0.43) L3MBTL1ATMKDM4EHDAC4AVPR1A
SCHEMBL21365509 0.97 L3MBTL1 (0.47) L3MBTL1ATMKDM4EHDAC4AVPR1A
SCHEMBL26053622 0.97 ATM (0.43) L3MBTL1ATMKDM4EHDAC4AVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed