SCHEMBL18708367

SCHEMBL18708367

c1ccc(-c2ccc(-n3c4ccccc4c4c5c6ccccc6n(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c5ccc43)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
HDAC4 P56524 1/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
AVPR1A P37288 1/20 0.36
HSP90AA1 P07900 1/20 0.35
MAPT P10636 1/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
RAB9A P51151 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
IL1R1 P14778 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18124851 1.00 ATM (0.43) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL23805714 1.00 ATM (0.43) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL20315781 1.00 ATM (0.43) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL26053622 1.00 ATM (0.43) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL26053729 1.00 ATM (0.43) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL20152142 0.99 L3MBTL1 (0.44) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL25965992 0.97 L3MBTL1 (0.49) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL17248190 0.97 L3MBTL1 (0.47) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL19769803 0.97 L3MBTL1 (0.47) ATML3MBTL1KDM4EHDAC4KMT2A
SCHEMBL21365509 0.97 L3MBTL1 (0.47) ATML3MBTL1KDM4EHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702420-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-18 US disclosed
US-11702420-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-18 US disclosed
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-01-19 US disclosed
US-20210323968-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-10-21 US disclosed
US-11117897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-09-14 US disclosed
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2021-05-20 US disclosed
US-10662196-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-05-26 US disclosed
US-20180182970-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-06-28 US disclosed
US-20180182970-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-06-28 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-05-17 US disclosed
US-20170098778-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE, ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-04-06 US disclosed
US-20170098778-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE, ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11117897-B2 Organic electroluminescent materials and devices ECI1, NDUFS3, NDUFV1 ATM 2475/4885L3MBTL1 2949/4885KDM4E 3164/4885
US-10662196-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, SLCO4C1 ATM 2986/4885L3MBTL1 2317/4885KDM4E 3377/4885
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, SOD1 ATM 2183/4885L3MBTL1 123/4885KDM4E 3351/4885
US-11702420-B2 Organic electroluminescent materials and devices ECI1, NDUFS3, NDUFV1 ATM 2475/4885L3MBTL1 2949/4885KDM4E 3164/4885
US-20170098778-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE, ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OR10J3, OCIAD1 ATM 4046/4885L3MBTL1 4765/4885KDM4E 4290/4885
US-20210323968-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ECI1, NDUFS3, NDUFV1 ATM 2475/4885L3MBTL1 2949/4885KDM4E 3164/4885
US-20180134718-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, SLCO4C1 ATM 2986/4885L3MBTL1 2317/4885KDM4E 3377/4885
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME CBR3, INTS9, CBR1 ATM 2844/4885L3MBTL1 208/4885KDM4E 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.