SCHEMBL25967800

SCHEMBL25967800

CC[C@@]1(C(C)C)O[C@@H](n2cc(C)c(=O)[nH]c2=O)C(OC(C)=O)[C@H]1OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ TK1 P04183 6/20 0.40
▸ RNASE1 P07998 1/20 0.38
▸ HPGD P15428 1/20 0.37
▸ TK2 O00142 3/20 0.37
▸ NT5M Q9NPB1 1/20 0.36
▸ BCHE P06276 1/20 0.35
▸ TYMP P19971 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11981102 0.88 TK1 (0.44) TK1RNASE1HPGDTK2NT5M
SCHEMBL14946306 0.88 TK1 (0.44) TK1RNASE1HPGDTK2NT5M
SCHEMBL25967797 0.87 TK1 (0.44) TK1HPGDTK2
SCHEMBL17356765 0.86 TK1 (0.41) TK1RNASE1HPGDTK2NT5M
SCHEMBL20394084 0.85 TK1 (0.36) TK1RNASE1TK2NT5MBCHE
SCHEMBL11981123 0.85 TK1 (0.42) TK1RNASE1HPGDTK2NT5M
SCHEMBL23152977 0.84 TK1 (0.41) TK1RNASE1HPGDTK2NT5M
SCHEMBL26135487 0.82 TK1 (0.42) TK1RNASE1HPGDTK2NT5M
SCHEMBL26135489 0.82 TK1 (0.42) TK1RNASE1HPGDTK2NT5M
SCHEMBL16648575 0.81 TK1 (0.38) TK1RNASE1HPGDTK2NT5M

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257413-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF RIKEN GENESIS CO., LTD. (JP) 2023-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257413-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF NSUN2, NSUN3, POLRMT TK1 1395/4885RNASE1 56/4885HPGD 4078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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