SCHEMBL25967806

SCHEMBL25967806

CC[C@@]1([C@H](C)O)O[C@H]2OC(C)(C)OC2[C@H]1OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ ALDH1A1 P00352 3/20 0.34
▸ IDO1 P14902 1/20 0.34
▸ HTT P42858 4/20 0.33
▸ HPGD P15428 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ BCHE P06276 3/20 0.32
▸ GSTP1 P09211 2/20 0.32
▸ ELANE P08246 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356766 1.00 KMT2A (0.38) KMT2AMEN1ALDH1A1IDO1HTT
SCHEMBL25967804 0.90 MEN1 (0.35) KMT2AMEN1ALDH1A1IDO1GSTP1
SCHEMBL25911629 0.88 KMT2A (0.37) KMT2AMEN1ALDH1A1IDO1HTT
SCHEMBL20484797 0.88 KMT2A (0.37) KMT2AMEN1ALDH1A1IDO1HTT
SCHEMBL1059333 0.88 KMT2A (0.37) KMT2AMEN1ALDH1A1IDO1HTT
SCHEMBL21085574 0.88 KMT2A (0.37) KMT2AMEN1ALDH1A1IDO1HTT
SCHEMBL2720695 0.84 KMT2A (0.37) KMT2AMEN1ALDH1A1IDO1HTT
SCHEMBL12306538 0.83 MEN1 (0.34) KMT2AMEN1ALDH1A1IDO1BCHE
SCHEMBL2719573 0.83 MEN1 (0.34) KMT2AMEN1ALDH1A1IDO1BCHE
SCHEMBL2717735 0.83 MEN1 (0.34) KMT2AMEN1ALDH1A1IDO1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257413-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF RIKEN GENESIS CO., LTD. (JP) 2023-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257413-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF NSUN2, NSUN3, POLRMT KMT2A 229/4885MEN1 933/4885ALDH1A1 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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