SCHEMBL25967804

SCHEMBL25967804

CC[C@@]1(C(C)C)O[C@H]2OC(C)(C)OC2[C@H]1OCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.33
▸ IDO1 P14902 1/20 0.33
▸ CCKBR P32239 1/20 0.31
▸ GSTP1 P09211 2/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ OPRM1 P35372 1/20 0.30
▸ OPRL1 P41146 1/20 0.30
▸ DHFR P00374 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17356766 0.90 KMT2A (0.38) MEN1KMT2AALDH1A1IDO1GSTP1
SCHEMBL25967806 0.90 KMT2A (0.38) MEN1KMT2AALDH1A1IDO1GSTP1
SCHEMBL2720695 0.83 KMT2A (0.37) MEN1KMT2AALDH1A1IDO1GSTP1
SCHEMBL13792726 0.82 MEN1 (0.32) MEN1KMT2A
SCHEMBL11981097 0.82 ALDH1A1 (0.36) MEN1KMT2AALDH1A1IDO1GSTP1
SCHEMBL10158872 0.82 ALDH1A1 (0.36) MEN1KMT2AALDH1A1IDO1GSTP1
SCHEMBL10158787 0.82 ALDH1A1 (0.36) MEN1KMT2AALDH1A1IDO1GSTP1
SCHEMBL16575320 0.82 ALDH1A1 (0.36) MEN1KMT2AALDH1A1IDO1GSTP1
SCHEMBL18561544 0.82 ALDH1A1 (0.36) MEN1KMT2AALDH1A1IDO1GSTP1
SCHEMBL1059333 0.81 KMT2A (0.37) MEN1KMT2AALDH1A1IDO1CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257413-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF RIKEN GENESIS CO., LTD. (JP) 2023-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257413-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE THEREOF NSUN2, NSUN3, POLRMT MEN1 933/4885KMT2A 229/4885ALDH1A1 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback