SCHEMBL25967893

SCHEMBL25967893

CCCCCCCCCCCCCCCCOC[C@@H](O)CO[Si](C)(C)C(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.56
HTT P42858 2/20 0.54
LPAR5 Q9H1C0 4/20 0.51
SPHK1 Q9NYA1 1/20 0.46
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
PLA2G2C Q5R387 3/20 0.41
LPAR1 Q92633 7/20 0.38
LPAR3 Q9UBY5 7/20 0.38
LPAR2 Q9HBW0 4/20 0.38
LPAR6 P43657 3/20 0.38
LPAR4 Q99677 3/20 0.38
P2RY10 O00398 1/20 0.38
MEN1 O00255 1/20 0.37
THRB P10828 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14762534 1.00 USP2 (0.56) USP2HTTLPAR5SPHK1CYP1A2
SCHEMBL25763110 1.00 USP2 (0.56) USP2HTTLPAR5SPHK1CYP1A2
SCHEMBL25763616 1.00 USP2 (0.56) USP2HTTLPAR5SPHK1CYP1A2
SCHEMBL9069638 1.00 USP2 (0.56) USP2HTTLPAR5SPHK1CYP1A2
SCHEMBL6113475 1.00 USP2 (0.56) USP2HTTLPAR5SPHK1CYP1A2
SCHEMBL25967662 1.00 USP2 (0.56) USP2HTTLPAR5SPHK1CYP1A2
SCHEMBL28854872 1.00 USP2 (0.56) USP2HTTLPAR5SPHK1CYP1A2
SCHEMBL25956316 1.00 USP2 (0.56) USP2HTTLPAR5SPHK1CYP1A2
Benzoic Acid SCHEMBL29020854 0.84 PLA2G4B (0.51) USP2HTTLPAR5
SCHEMBL31362242 0.82 GPR84 (0.41) USP2HTTSPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4537828-A2 PHOSPHOLIPID COMPOUNDS AND USES THEREOF Gilead Sciences, Inc. (US) 2025-04-16 EP disclosed
EP-4200301-B1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES INC (US) 2025-02-26 EP disclosed
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 US disclosed
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 US disclosed
EP-4200301-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2023-06-28 EP disclosed
WO-2022046631-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2022-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 USP2 4298/4885HTT 3678/4885LPAR5 66/4885
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 USP2 4298/4885HTT 3678/4885LPAR5 66/4885
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 USP2 4298/4885HTT 3678/4885LPAR5 66/4885
US-11773122-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 USP2 4298/4885HTT 3678/4885LPAR5 66/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.