⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25966721 | 0.81 | DRD2 (0.31) | — | |
| SCHEMBL17249513 | 0.77 | PDE10A (0.35) | — | |
| SCHEMBL20073549 | 0.75 | PDE10A (0.40) | — | |
| SCHEMBL14925516 | 0.74 | DRD2 (0.35) | — | |
| SCHEMBL25966719 | 0.73 | PDCD1 (0.37) | — | |
| SCHEMBL23594254 | 0.70 | GRM5 (0.34) | — | |
| SCHEMBL22381072 | 0.70 | KDM4E (0.35) | — | |
| SCHEMBL26805578 | 0.70 | — | — | |
| SCHEMBL24941734 | 0.70 | — | — | |
| SCHEMBL24309011 | 0.69 | HTR4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250088-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
| US-20230250060-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |