Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.45 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18900267 | 0.88 | TRPV4 (0.46) | TRPV4KHKTTRALBALDH1A1 | |
| SCHEMBL799564 | 0.88 | TRPV4 (0.46) | TRPV4KHKTTRALBALDH1A1 | |
| SCHEMBL17672794 | 0.86 | TRPV4 (0.56) | TRPV4KHKTTRALBALDH1A1 | |
| SCHEMBL21212728 | 0.82 | TTR (0.40) | TRPV4TTRALBXDHDYRK1A | |
| SCHEMBL3324301 | 0.80 | TRPV4 (0.41) | TRPV4KHKTTRALB | |
| SCHEMBL2474467 | 0.80 | ALDH1A1 (0.46) | TRPV4KHKALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL21763267 | 0.79 | TTR (0.42) | TRPV4TTRALBXDHDYRK1A | |
| SCHEMBL6739415 | 0.76 | ALDH1A1 (0.44) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL2783854 | 0.73 | TRPV4 (0.56) | TRPV4KHKALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL6651303 | 0.73 | TRPV4 (0.71) | TRPV4KHKALDH1A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257362-A1 | TRIAZOLONE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257362-A1 | TRIAZOLONE COMPOUND | WNK3, SLC10A1, WNK2 | TRPV4 166/4885KHK 1077/4885TTR 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.