Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.86 |
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769005 | 0.82 | ALDH1A1 (0.72) | ALDH1A1KDM4EATMPOLBNPSR1 | |
| SCHEMBL3704635 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KDM4EATMPOLBNPSR1 | |
| SCHEMBL16226753 | 0.81 | ALDH1A1 (0.66) | ALDH1A1KDM4EATMPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL3716083 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KDM4EATMPOLBNPSR1 | |
| Cyclopentanamine SCHEMBL5925376 | 0.81 | KDM4E (0.59) | ALDH1A1KDM4EATMPOLBNPSR1 | |
| Hydrochloric Acid SCHEMBL7405455 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KDM4EATMPOLBNPSR1 | |
| SCHEMBL31669175 | 0.80 | ALDH1A1 (0.74) | ALDH1A1KDM4EATMPOLBNPSR1 | |
| Hydrochloric Acid SCHEMBL3716147 | 0.80 | CHRM1 (0.60) | ALDH1A1KDM4EATMPOLBNPSR1 | |
| SCHEMBL3706431 | 0.79 | GLA (0.62) | ALDH1A1KDM4EATMPOLBCHRM1 | |
| SCHEMBL3705468 | 0.79 | KDM4E (0.57) | ALDH1A1KDM4EATMCHRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257350-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | THE CLEVELAND CLINIC FOUNDATION | 2023-08-17 | — | — | US | disclosed |
| US-20230257350-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | THE CLEVELAND CLINIC FOUNDATION | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257350-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | CHAT, DCX, GAP43 | ALDH1A1 611/4885KDM4E 3073/4885ATM 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.