Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3716083 | 0.99 | ALDH1A1 (0.63) | ALDH1A1KDM4EC5AR1CHRM1ATM | |
| SCHEMBL3705468 | 0.84 | KDM4E (0.57) | ALDH1A1KDM4EC5AR1CHRM1ATM | |
| SCHEMBL3706431 | 0.84 | GLA (0.62) | ALDH1A1KDM4EC5AR1CHRM1ATM | |
| Hydrochloric Acid SCHEMBL3704470 | 0.83 | KDM4E (0.56) | ALDH1A1KDM4EC5AR1CHRM1ATM | |
| Hydrochloric Acid SCHEMBL3708648 | 0.82 | C5AR1 (0.58) | ALDH1A1KDM4EC5AR1CHRM1ATM | |
| SCHEMBL25967987 | 0.82 | ALDH1A1 (0.86) | ALDH1A1KDM4ECHRM1ATMDRD2 | |
| Hydrochloric Acid SCHEMBL3716147 | 0.81 | CHRM1 (0.60) | ALDH1A1KDM4EC5AR1CHRM1ATM | |
| SCHEMBL3708205 | 0.81 | C5AR1 (0.61) | ALDH1A1KDM4EC5AR1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL3703420 | 0.80 | C5AR1 (0.60) | ALDH1A1KDM4EC5AR1KMT2ATDP1 | |
| SCHEMBL3712719 | 0.78 | MAPT (0.74) | ALDH1A1MAPTDRD2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |