Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25970714 | 0.90 | TRPA1 (0.63) | TRPA1 | |
| SCHEMBL25970092 | 0.90 | TRPA1 (0.56) | TRPA1 | |
| SCHEMBL25969330 | 0.89 | TRPA1 (0.55) | TRPA1 | |
| SCHEMBL25974095 | 0.87 | TRPA1 (0.55) | TRPA1 | |
| SCHEMBL25969982 | 0.87 | TRPA1 (0.53) | TRPA1GAA | |
| SCHEMBL25969833 | 0.87 | TRPA1 (0.53) | TRPA1 | |
| SCHEMBL25969977 | 0.87 | TRPA1 (0.53) | TRPA1 | |
| SCHEMBL25970094 | 0.87 | TRPA1 (0.58) | TRPA1 | |
| SCHEMBL25969967 | 0.87 | TRPA1 (0.53) | TRPA1 | |
| SCHEMBL25970615 | 0.86 | TRPA1 (0.59) | TRPA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154139-A1 | PYRIDAZINONE COMPOUNDS AS TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC | 2025-05-15 | — | — | US | disclosed |
| WO-2023150591-A2 | PYRIDAZINONE COMPOUNDS AS TRPA1 INHIBITORS | D.E. SHAW RESEARCH, LLC (US) | 2023-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154139-A1 | PYRIDAZINONE COMPOUNDS AS TRPA1 INHIBITORS | TRPA1, TRPV1, TRPV5 | TRPA1 1/4885GAA 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.