SCHEMBL25969148

SCHEMBL25969148

Cc1cc(F)c(N2CCC(COc3ccc(F)cc3CC=O)CC2)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 15/20 0.46
RBP4 P02753 3/20 0.40
TTR P02766 2/20 0.40
C5AR1 P21730 1/20 0.37
DCPS Q96C86 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20612909 0.84 FFAR4 (0.44) FFAR4RBP4TTRDCPS
SCHEMBL25969068 0.82 FFAR4 (0.50) FFAR4RBP4TTR
SCHEMBL20613101 0.82 FFAR4 (0.43) FFAR4RBP4TTRDCPS
SCHEMBL20612938 0.80 FFAR4 (0.44) FFAR4RBP4TTR
SCHEMBL25968743 0.74 FFAR4 (0.40) FFAR4C5AR1DCPS
SCHEMBL20612921 0.74 FFAR4 (0.44) FFAR4
SCHEMBL20612907 0.74 FFAR4 (0.41) FFAR4C5AR1DCPS
SCHEMBL20612937 0.73 FFAR4 (0.42) FFAR4DCPS
SCHEMBL20613002 0.73 FFAR4 (0.43) FFAR4
SCHEMBL20714057 0.73 FFAR4 (0.43) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421454-B9 PIPERIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2023-08-09 EP disclosed