Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 10/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 5/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25339817 | 1.00 | GFER (0.33) | GFERIRAK4BRAFCYP17A1RORC | |
| SCHEMBL23744953 | 0.88 | OPRM1 (0.39) | IRAK4RORC | |
| SCHEMBL25338181 | 0.86 | AAK1 (0.34) | GFERIRAK4RORC | |
| SCHEMBL21997531 | 0.86 | IRAK4 (0.39) | GFERIRAK4RORC | |
| SCHEMBL25969167 | 0.86 | GFER (0.33) | GFERIRAK4RORCBRD9 | |
| SCHEMBL23744955 | 0.86 | IRAK4 (0.39) | GFERIRAK4RORC | |
| SCHEMBL25339977 | 0.86 | GFER (0.33) | GFERIRAK4RORCBRD9 | |
| SCHEMBL23744954 | 0.86 | GFER (0.33) | GFERIRAK4RORCBRD9 | |
| SCHEMBL21996690 | 0.86 | GFER (0.33) | GFERIRAK4RORCBRD9 | |
| SCHEMBL25969140 | 0.86 | AAK1 (0.34) | GFERIRAK4RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365562-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-11-16 | — | — | US | disclosed |
| US-20230365562-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-11-16 | — | — | US | disclosed |
| WO-2023147594-A2 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365562-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | GFER 2248/4885IRAK4 4/4885BRAF 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.