Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15999099 | 0.86 | SCN9A (0.49) | KDM4CKMOSCN9ASCN10AKDM4E | |
| SCHEMBL30547754 | 0.83 | KMO (0.43) | KDM4CKMOKDM4EHPGDHSD17B10 | |
| SCHEMBL25966972 | 0.82 | KDM4C (0.48) | KDM4CKMOKDM4EHPGDHSD17B10 | |
| SCHEMBL30622483 | 0.79 | HPGD (0.41) | KDM4CKMOKDM4EHPGDHSD17B10 | |
| SCHEMBL15999085 | 0.78 | KDM4E (0.40) | KDM4CKMOKDM4EHPGDHSD17B10 | |
| SCHEMBL30622472 | 0.78 | POLB (0.41) | KDM4CKMOKDM4EHPGDHSD17B10 | |
| SCHEMBL30622541 | 0.78 | KDM4C (0.51) | KDM4CKMOKDM4EHPGDHSD17B10 | |
| SCHEMBL15999091 | 0.78 | KDM4E (0.39) | KDM4CKMOCCR1SCN9ASCN10A | |
| SCHEMBL15999071 | 0.78 | CYP11B2 (0.46) | CCR1SCN9ASCN10AKDM4EHSD17B10 | |
| SCHEMBL15999052 | 0.77 | PTGER4 (0.50) | CCR1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250088-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250088-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | KDM4C 4078/4885KMO 4168/4885CCR1 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.