Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792784 | 0.91 | MAPT (0.49) | MAPTMAPK1GAACTBP2KMT2A | |
| SCHEMBL10544357 | 0.82 | XPO1 (0.52) | MAPTMAPK1GAACTBP2KMT2A | |
| SCHEMBL406058 | 0.81 | MAOB (0.58) | MAPTMAPK1CTBP2KMT2ASMN1; SMN2 | |
| SCHEMBL27006313 | 0.81 | MAPT (0.54) | MAPTGAAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4755209 | 0.81 | CES2 (0.55) | MAPTMAPK1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7059318 | 0.79 | PLAAT3 (0.52) | MAPTMAPK1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL7640165 | 0.78 | CTBP2 (0.51) | CTBP2KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7643117 | 0.78 | PLAAT3 (0.53) | MAPTMAPK1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4325061 | 0.77 | EPHX2 (0.52) | MAPTMAPK1GAACTBP2KMT2A | |
| SCHEMBL15682692 | 0.75 | RXFP1 (0.53) | MAPTGAAKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011144338-A1 | PYRAZOLE DERIVATIVES AS S1P1 AGONISTS | ALMIRALL, S.A. (ES) | 2011-11-24 | — | — | WO | disclosed |