Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | TP53 | P04637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | SMOX | Q9NWM0 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30516216 | 0.99 | KDM4E (0.58) | KDM4EALDH1A1TP53MAPTHTT | |
| SCHEMBL25974223 | 0.84 | TP53 (0.53) | KDM4EALDH1A1TP53MAPTHTT | |
| SCHEMBL25970334 | 0.84 | OPRK1 (0.66) | KDM4EALDH1A1TP53MAPTHTT | |
| Hydrochloric Acid SCHEMBL30516229 | 0.83 | OPRK1 (0.64) | KDM4EALDH1A1TP53MAPTHTT | |
| SCHEMBL25970233 | 0.82 | OPRK1 (0.69) | KDM4EALDH1A1TP53MAPTHTT | |
| SCHEMBL1718891 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1TP53MAPTHTT | |
| SCHEMBL1718028 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1TP53MAPTHTT | |
| SCHEMBL25970331 | 0.79 | OPRK1 (0.68) | KDM4EALDH1A1TP53MAPTHTT | |
| SCHEMBL25970464 | 0.79 | OPRK1 (0.62) | KDM4EALDH1A1TP53MAPTHTT | |
| SCHEMBL1718477 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1TP53MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141866-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | WO | disclosed |