Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.86 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.86 |
| ▸ | TSHR | P16473 | 1/20 | 0.86 |
| ▸ | CA1 | P00915 | 2/20 | 0.83 |
| ▸ | CA2 | P00918 | 2/20 | 0.83 |
| ▸ | BCHE | P06276 | 1/20 | 0.83 |
| ▸ | ACHE | P22303 | 1/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Parathion SCHEMBL26857 | 0.93 | ALDH1A1 (1.00) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR | |
| Parathion SCHEMBL8779525 | 0.91 | ALDH1A1 (0.97) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR | |
| Parathion SCHEMBL10585964 | 0.91 | ALDH1A1 (0.97) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR | |
| Parathion SCHEMBL10585960 | 0.91 | ALDH1A1 (0.97) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR | |
| Parathion SCHEMBL8960276 | 0.91 | ALDH1A1 (0.97) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR | |
| Parathion SCHEMBL20271121 | 0.91 | ALDH1A1 (0.97) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR | |
| Parathion SCHEMBL10447032 | 0.91 | ALDH1A1 (0.97) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR | |
| Parathion SCHEMBL8960270 | 0.91 | ALDH1A1 (0.97) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR | |
| Parathion SCHEMBL10436147 | 0.91 | ALDH1A1 (0.97) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR | |
| Parathion SCHEMBL17981469 | 0.91 | ALDH1A1 (0.97) | MAPK1ALDH1A1CYP3A4HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2568807-A1 | PHENOXYALKYL PYRIDINIUM OXIME THERAPEUTICS FOR TREATMENT OF ORGANOPHOSPHATE POISONING | Mississipi State University (US) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011142826-A1 | PHENOXYALKYL PYRIDINIUM OXIME THERAPEUTICS FOR TREATMENT OF ORGANOPHOSPHATE POISONING | MISSISSIPI STATE UNIVERSITY (US) | 2011-11-17 | — | — | WO | disclosed |