Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | F13A1 | P00488 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | TGM1 | P22735 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.41 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918583 | 0.94 | F13A1 (0.43) | SMN1; SMN2NPC1RAB9AF13A1TGM2 | |
| SCHEMBL14918832 | 0.89 | F13A1 (0.51) | SMN1; SMN2NPC1RAB9AF13A1TGM2 | |
| SCHEMBL2597039 | 0.89 | F13A1 (0.51) | SMN1; SMN2NPC1RAB9AF13A1TGM2 | |
| Iodomethane SCHEMBL27928620 | 0.88 | F13A1 (0.49) | SMN1; SMN2NPC1RAB9AF13A1TGM2 | |
| Iodomethane SCHEMBL14917750 | 0.88 | F13A1 (0.49) | SMN1; SMN2NPC1RAB9AF13A1TGM2 | |
| SCHEMBL2597121 | 0.84 | GPR119 (0.37) | SMN1; SMN2CYP2C9GPR119 | |
| SCHEMBL27910902 | 0.81 | GRIN2B (0.45) | SMN1; SMN2NPC1RAB9AF13A1TGM2 | |
| SCHEMBL27928622 | 0.81 | GRIN2B (0.45) | SMN1; SMN2NPC1RAB9AF13A1TGM2 | |
| SCHEMBL2598372 | 0.78 | GPR119 (0.49) | CYP2C9GPR119STS | |
| SCHEMBL2597117 | 0.78 | FPR2 (0.35) | HTTCYP2C9GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571864-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146335-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2011-11-24 | — | — | WO | disclosed |