Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23880056 | 0.89 | ALDH1A1 (0.48) | ALDH1A1PLA2G1BATG4BRBP4PDE10A | |
| SCHEMBL23880060 | 0.83 | SCN9A (0.46) | ALDH1A1PLA2G1BATG4BRBP4PDE10A | |
| SCHEMBL25972074 | 0.83 | ALDH1A1 (0.45) | ALDH1A1PLA2G1BATG4BRBP4PDE10A | |
| SCHEMBL23880061 | 0.76 | SCN9A (0.49) | ALDH1A1PLA2G1BATG4BSCN9AMEN1 | |
| SCHEMBL25972070 | 0.76 | ALDH1A1 (0.49) | ALDH1A1PLA2G1BATG4BRBP4SCN9A | |
| SCHEMBL23880057 | 0.76 | SCN9A (0.47) | ALDH1A1PLA2G1BATG4BRBP4SCN9A | |
| SCHEMBL25972082 | 0.76 | HPGD (0.50) | ALDH1A1PLA2G1BATG4BRBP4MEN1 | |
| SCHEMBL2733495 | 0.74 | SMN1; SMN2 (0.65) | ALDH1A1SCN9AMEN1KMT2AMAPT | |
| SCHEMBL10203177 | 0.73 | L3MBTL3 (0.67) | ALDH1A1MEN1KMT2AHRH3L3MBTL3 | |
| SCHEMBL23880068 | 0.72 | SCN9A (0.49) | ALDH1A1SCN9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725012-B2 | Imidazo[1,5-a]pyrazine derivatives as PI3K δ inhibitors | BEIGENE, LTD. (KY) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725012-B2 | Imidazo[1,5-a]pyrazine derivatives as PI3K δ inhibitors | PIK3CD, PIK3R5, PIK3CA | ALDH1A1 1955/4885PLA2G1B 1312/4885ATG4B 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.