SCHEMBL25972704

SCHEMBL25972704

c1ccc2c(-n3c4ccccc4c4cc(-c5cccc6cccc(-c7ccc8c(c7)c7ccccc7n8-c7cccc8ccccc78)c56)ccc43)cccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
ALDH1A1 P00352 3/20 0.36
MAPK1 P28482 3/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HIF1A Q16665 1/20 0.36
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GSK3A P49840 1/20 0.35
GSK3B P49841 1/20 0.35
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18717918 0.91 POLB (0.45) POLBALDH1A1MAPK1TSHRHSD17B10
SCHEMBL17953802 0.89 POLB (0.39) POLBALDH1A1MAPK1TSHRHSD17B10
SCHEMBL25972709 0.89 PDE6D (0.38) POLBALDH1A1MAPK1TSHRHSD17B10
SCHEMBL20149463 0.89 POLB (0.43) POLBALDH1A1MAPK1HSD17B10TP53
SCHEMBL31139498 0.88 POLB (0.42) POLBALDH1A1MAPK1TSHRHSD17B10
SCHEMBL12088908 0.88 POLB (0.42) POLBALDH1A1MAPK1TSHRHSD17B10
SCHEMBL17953805 0.88 POLB (0.40) POLBALDH1A1MAPK1TSHRHSD17B10
SCHEMBL10130201 0.87 POLB (0.42) POLBALDH1A1CNR1CNR2TDP1
SCHEMBL25474002 0.87 KDM4E (0.44) POLBALDH1A1CNR1CNR2ATM
SCHEMBL25474000 0.87 KDM4E (0.44) POLBALDH1A1CNR1CNR2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250048-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-10 US disclosed
US-20230250048-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250048-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE NOS1, NOM1, NCF1 POLB 2843/4885ALDH1A1 1717/4885MAPK1 220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.