Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447248 | 0.87 | SIGMAR1 (0.38) | ALDH1A1HPGDKDM4CAOC3KDM4E | |
| SCHEMBL23447607 | 0.85 | MAPT (0.46) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL23447579 | 0.78 | TMEM97 (0.40) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL23447599 | 0.78 | SIGMAR1 (0.38) | ALDH1A1MAPTAOC3KDM4ESMN1; SMN2 | |
| SCHEMBL23447580 | 0.78 | PDE10A (0.41) | ALDH1A1MAPTHTTKMT2AKDM4E | |
| SCHEMBL23447254 | 0.77 | TMEM97 (0.39) | MAPTSMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL23447656 | 0.76 | PDE10A (0.32) | — | |
| SCHEMBL23447600 | 0.75 | HSD11B1 (0.39) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL25972976 | 0.74 | SIGMAR1 (0.44) | ALDH1A1MAPTAOC3NPC1RAB9A | |
| SCHEMBL23447270 | 0.73 | PDE10A (0.38) | MAPTHTTAOC3KDM4ECASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065564-B1 | [ (1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL) OXY ] ACETIC ACID DERIVATIVES AND SALTS THEREOF, USEFUL OR CULTIVATING AGENTS CONTAINING THEM, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS SAFENERS | BAYER AG (DE) | 2023-07-26 | — | — | EP | disclosed |