Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CCR9 | P51686 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973046 | 0.89 | KDM4E (0.44) | CRHR1MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL23447255 | 0.85 | CRHR1 (0.52) | CRHR1MAPTKDM4EALDH1A1HSD11B1 | |
| SCHEMBL25972585 | 0.83 | KDM4E (0.53) | MAPTKDM4EALDH1A1LMNAEGFR | |
| SCHEMBL24409982 | 0.81 | MAPT (0.40) | MAPTKDM4EALDH1A1LMNAEGFR | |
| SCHEMBL23447273 | 0.79 | CRHR1 (0.54) | CRHR1HSD11B1CNR1 | |
| SCHEMBL24406716 | 0.79 | KDM4E (0.43) | MAPTKDM4EALDH1A1LMNAEGFR | |
| SCHEMBL24407476 | 0.79 | CRHR1 (0.48) | CRHR1MAPTKDM4ELMNAHSD11B1 | |
| SCHEMBL24425230 | 0.78 | MAPT (0.44) | MAPTKDM4EEGFRCNR1CYP3A4 | |
| SCHEMBL24409990 | 0.76 | KDM4E (0.40) | MAPTKDM4EALDH1A1LMNAEGFR | |
| SCHEMBL24406766 | 0.76 | CCR9 (0.39) | MAPTKDM4EALDH1A1LMNACCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065564-B1 | [ (1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL) OXY ] ACETIC ACID DERIVATIVES AND SALTS THEREOF, USEFUL OR CULTIVATING AGENTS CONTAINING THEM, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS SAFENERS | BAYER AG (DE) | 2023-07-26 | — | — | EP | disclosed |