Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 11/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MARS1 | P56192 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23447263 | 0.88 | CRHR1 (0.40) | CRHR1HSD11B1 | |
| SCHEMBL25973005 | 0.85 | CRHR1 (0.48) | CRHR1HSD11B1CNR1KDM4EMAPT | |
| SCHEMBL23447194 | 0.83 | NR1H2 (0.45) | CRHR1CNR1CNR2KDM4EMAPT | |
| SCHEMBL23447273 | 0.82 | CRHR1 (0.54) | CRHR1HSD11B1CNR1CNR2 | |
| SCHEMBL25973046 | 0.74 | KDM4E (0.44) | CRHR1KDM4EMAPTALDH1A1 | |
| SCHEMBL25972543 | 0.73 | HSD11B1 (0.42) | CRHR1HSD11B1KDM4EALDH1A1HPGD | |
| SCHEMBL23447092 | 0.71 | CRHR1 (0.41) | CRHR1HSD11B1CNR1CNR2 | |
| SCHEMBL24407540 | 0.70 | CRHR1 (0.50) | CRHR1HSD11B1CNR1CNR2 | |
| SCHEMBL24407449 | 0.70 | CRHR1 (0.50) | CRHR1HSD11B1CNR1KDM4EMAPT | |
| SCHEMBL23447218 | 0.69 | HSD11B1 (0.40) | CRHR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021105101-A1 | [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACID DERIVATIVES AND SALTS THEREOF, CROP PROTECTION COMPOSITIONS COMPRISING THEM, METHODS FOR PRODUCING THEM AND USE THEREOF AS SAFENERS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-03 | — | — | WO | disclosed |