⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29101107 | 0.85 | TSHR (0.33) | — | |
| SCHEMBL609000 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL638840 | 0.80 | — | — | |
| SCHEMBL892657 | 0.79 | — | — | |
| SCHEMBL609001 | 0.79 | — | — | |
| SCHEMBL10842062 | 0.77 | — | — | |
| SCHEMBL10919035 | 0.77 | — | — | |
| SCHEMBL10878549 | 0.77 | CA2 (0.39) | — | |
| SCHEMBL1818354 | 0.76 | — | — | |
| SCHEMBL9314301 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478391-B | Ornidazole ester prodrug, pharmaceutical composition, and preparation method and application thereof | 南京锐志生物医药有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-114436972-A | Pabendazole derivative and preparation method and application thereof | 山东大学 | 2022-05-06 | — | — | CN | claimed |
| CN-122070276-A | Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same | 人类生物科学股份有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-4705289-A1 | PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF | Terran Biosciences Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12421260-B2 | Neurokinin-1 antagonist | SHANGHAI SHENGDI PHARMACEUTICAL CO., LTD (CN) | 2025-09-23 | — | — | US | disclosed |
| US-20250206724-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-06-26 | — | — | US | disclosed |
| EP-4499612-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2025-02-05 | — | — | EP | disclosed |
| CN-118974020-A | Substituted 3-aminoindazole derivatives as kinase inhibitors | 内尔维亚诺医疗科学公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-115677718-B | Methyl methylamine derivative preparation, pharmaceutical composition and application thereof | 武汉思瓴生物科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-2024226691-A1 | PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF | TERRAN BIOSCIENCES INC. (US) | 2024-10-31 | — | — | WO | disclosed |
| CN-114728883-B | Ibuprofen ester prodrug, pharmaceutical composition, preparation method and application | 南京海融医药科技股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2009115427-A1 | PYRROLIDINYL DERIVATIVES AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2009-09-24 | — | — | WO | disclosed |
| EP-2074107-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008057254-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-05-15 | — | — | WO | disclosed |
| US-5120841-A | Antibiotics for easy absorption | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0104984-B1 | VINYLCARBAMIC ACID ESTERS AND THEIR PREPARATION | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1990-05-16 | — | — | EP | disclosed |
| EP-0128029-B1 | CEPHALOSPORIN ESTER DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |
| EP-0128029-A2 | Cephalosporin ester derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-12-12 | — | — | EP | disclosed |
| EP-0104984-A2 | Vinylcarbamic acid esters and their preparation | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1984-04-04 | — | — | EP | disclosed |
| US-4120888-A | REACTING PHOSGENE WITH AN EPOXY | MINEREC CORPORATION (US) | 1978-10-17 | — | — | US | disclosed |