SCHEMBL2597345

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1618936	0.90	ALDH1A1 (0.42)	ALDH1A1ERN1KDM4ERAB9AMAPT
	SCHEMBL2700325	0.87	ALDH1A1 (0.42)	ALDH1A1ERN1KDM4ERAB9AMAPT
	SCHEMBL14726040	0.82	ERN1 (0.45)	ALDH1A1ERN1KDM4EMAPTTUBB1
	SCHEMBL1619656	0.81	ALDH1A1 (0.56)	ALDH1A1ERN1KDM4EMAPTTRIM24
	SCHEMBL9155251	0.80	KDM4E (0.56)	ALDH1A1ERN1KDM4ERAB9AMAPT
	SCHEMBL5882846	0.79	ALDH1A1 (0.65)	ALDH1A1ERN1KDM4ERAB9AMAPT
	SCHEMBL13095974	0.78	BRD4 (0.42)	ALDH1A1MAPTBRD4TUBB1MEN1
	SCHEMBL2700219	0.77	ERN1 (0.39)	ALDH1A1ERN1KDM4ERAB9AMAPT
	SCHEMBL5285862	0.76	ERN1 (0.51)	ERN1KDM4ERAB9AMAPTTUBB1
	SCHEMBL13085607	0.75	MEN1 (0.40)	ALDH1A1BRD4L3MBTL1TUBB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.