SCHEMBL2597368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1618513	0.89	MEN1 (0.37)	F10F7F2PRSS1PRSS2
	SCHEMBL12185986	0.85	ALDH1A1 (0.43)	KCNH2F10F7F2PRSS1
	SCHEMBL2701454	0.83	MEN1 (0.33)	F10F7F2PRSS1PRSS2
	SCHEMBL3464005	0.80	F10 (0.43)	F10F7PRSS1PRSS2PRSS3
	SCHEMBL13162156	0.79	CA12 (0.38)	F10F7HIF1AKCNA5ALDH1A1
	SCHEMBL5883488	0.76	MEN1 (0.42)	F10HIF1AALDH1A1LMNAGAA
	SCHEMBL12185966	0.75	F7 (0.38)	F10F7F2PRSS1PRSS2
	SCHEMBL5883565	0.75	MMP2 (0.41)	KCNA5ALDH1A1LMNAGAASGMS2
	SCHEMBL1619764	0.74	MEN1 (0.39)	F10F7HIF1AALDH1A1LMNA
	SCHEMBL7149887	0.73	F10 (0.43)	F10F7PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.