Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 5/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426690 | 0.82 | CHRM5 (0.54) | CHRM5CHRM1CHRM4CHRM3DRD2 | |
| SCHEMBL9426486 | 0.81 | CHRM5 (0.52) | CHRM5CHRM1CHRM4CHRM3DRD2 | |
| SCHEMBL25973990 | 0.80 | CHRM5 (0.52) | CHRM5CHRM1CHRM4CHRM3DRD2 | |
| SCHEMBL22495318 | 0.75 | POLB (0.55) | CHRM5CHRM1CHRM4CHRM3DRD2 | |
| SCHEMBL4758040 | 0.74 | CHRM5 (0.64) | CHRM5CHRM1CHRM4CHRM3DRD2 | |
| SCHEMBL20563412 | 0.74 | NPC1 (0.56) | CHRM5CHRM1CHRM4CHRM3DRD2 | |
| SCHEMBL13652111 | 0.72 | CHRM1 (0.44) | CHRM5CHRM1CHRM4CHRM3DRD2 | |
| SCHEMBL3952933 | 0.71 | CHRM5 (0.54) | CHRM5CHRM1CHRM4CHRM3DRD2 | |
| SCHEMBL9426611 | 0.71 | HTR2A (0.42) | CHRM5CHRM1CHRM4CHRM3DRD2 | |
| Bromide SCHEMBL3950871 | 0.71 | CHRM5 (0.53) | CHRM5CHRM1CHRM4CHRM3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141721-A1 | ANTICHOLINERGIC COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS | UNIVERSITY OF MONTRÉAL (CA) | 2023-08-03 | — | — | WO | disclosed |