Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 5/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426690 | 0.89 | CHRM5 (0.54) | CHRM5CHRM1CHRM4CHRM3CHRM2 | |
| SCHEMBL9426486 | 0.85 | CHRM5 (0.52) | CHRM5CHRM1CHRM4CHRM3CHRM2 | |
| SCHEMBL25973998 | 0.80 | CHRM5 (0.55) | CHRM5CHRM1CHRM4CHRM3CHRM2 | |
| SCHEMBL13652111 | 0.77 | CHRM1 (0.44) | CHRM5CHRM1CHRM4CHRM3CHRM2 | |
| SCHEMBL9426611 | 0.76 | HTR2A (0.42) | CHRM5CHRM1CHRM4CHRM3CHRM2 | |
| SCHEMBL3900689 | 0.75 | OPRM1 (0.58) | CHRM5CHRM1CHRM4CHRM3CHRM2 | |
| SCHEMBL4758040 | 0.73 | CHRM5 (0.64) | CHRM5CHRM1CHRM4CHRM3CHRM2 | |
| SCHEMBL9426661 | 0.72 | TRPM8 (0.46) | DRD2OPRM1SLC6A4ADRB1ADRA2A | |
| SCHEMBL8210819 | 0.71 | CHRM5 (0.61) | CHRM5CHRM1CHRM4CHRM3CHRM2 | |
| SCHEMBL8209857 | 0.70 | CHRM5 (0.60) | CHRM5CHRM1CHRM4CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141721-A1 | ANTICHOLINERGIC COMPOUNDS FOR USE IN TREATING NEUROMUSCULAR DISORDERS | UNIVERSITY OF MONTRÉAL (CA) | 2023-08-03 | — | — | WO | disclosed |