SCHEMBL2597415

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1621026	0.87	ALDH1A1 (0.47)	ALDH1A1GAASGMS2LMNAMMP2
	SCHEMBL12185986	0.82	ALDH1A1 (0.43)	ALDH1A1GAASGMS2LMNAMMP2
	SCHEMBL2701254	0.80	ALDH1A1 (0.41)	ALDH1A1GAASGMS2LMNAFPR1
	SCHEMBL2868724	0.73	ALDH1A1 (0.37)	ALDH1A1GAASGMS2LMNAMEN1
	SCHEMBL5883488	0.71	MEN1 (0.42)	ALDH1A1GAALMNAMMP2FPR1
	SCHEMBL6876129	0.71	F10 (0.39)	ALDH1A1GAALMNAMEN1KMT2A
	SCHEMBL1618513	0.70	MEN1 (0.37)	ALDH1A1GAAMMP2FPR1FPR2
	SCHEMBL16055010	0.70	MAPT (0.47)	ALDH1A1GAASGMS2LMNAMEN1
	SCHEMBL1619764	0.70	MEN1 (0.39)	ALDH1A1GAALMNAMMP2FPR1
	SCHEMBL2597368	0.68	KCNH2 (0.35)	ALDH1A1GAASGMS2LMNAMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.