Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25974324 | 0.83 | MKNK1 (0.33) | OXTRKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL14033406 | 0.83 | KMT2A (0.36) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL25974426 | 0.79 | MKNK2 (0.37) | KMT2A | |
| SCHEMBL25974443 | 0.76 | OXTR (0.33) | OXTRKMT2AMEN1MAPTHDAC4 | |
| SCHEMBL13086666 | 0.76 | TUBB1 (0.39) | PDE2APDE10AOXTRKMT2AMEN1 | |
| SCHEMBL25974321 | 0.75 | MKNK2 (0.35) | OXTRBACE1AVPR1A | |
| SCHEMBL25974440 | 0.74 | OXTR (0.32) | OXTRAVPR1A | |
| SCHEMBL6519254 | 0.74 | RAPGEF4 (0.32) | HDAC4RAPGEF4 | |
| SCHEMBL25974427 | 0.73 | MKNK2 (0.37) | OXTRAVPR1A | |
| SCHEMBL25974428 | 0.72 | OXTR (0.46) | OXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |