Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20444036 | 0.78 | KMT2A (0.34) | HTR3AKDM4ETOP2AKMT2APDE1A | |
| SCHEMBL11287052 | 0.76 | KDM4E (0.33) | HTR3AKDM4ETOP2AKMT2APDE1A | |
| SCHEMBL20176157 | 0.76 | KDM4E (0.36) | HTR3AKDM4ETOP2AKMT2APDE1A | |
| SCHEMBL12042945 | 0.65 | — | — | |
| SCHEMBL19698900 | 0.65 | ADORA2B (0.34) | KDM4ETOP2APDE1CBPTF | |
| SCHEMBL1008763 | 0.65 | GCK (0.35) | KDM4E | |
| SCHEMBL411297 | 0.64 | ABCB1 (0.41) | PDE1APDE1BPDE1C | |
| SCHEMBL6741169 | 0.64 | KMO (0.41) | KDM4EPDE1APDE1BPDE1C | |
| SCHEMBL24504750 | 0.64 | DRD4 (0.35) | — | |
| SCHEMBL16050701 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |