SCHEMBL25975120

SCHEMBL25975120

CCCCCCCCCCCCCCCCCCOCCCOP(=O)(O)OC[C@H]1O[C@@](C)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 6/20 0.39
▸ FGFR1 P11362 1/20 0.37
▸ POLRMT O00411 1/20 0.37
▸ TRPM2 O94759 1/20 0.36
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25970023 1.00 ADK (0.39) ADKFGFR1POLRMTTRPM2CYP3A4
SCHEMBL25970025 1.00 ADK (0.39) ADKFGFR1POLRMTTRPM2CYP3A4
SCHEMBL25974764 1.00 ADK (0.39) ADKFGFR1POLRMTTRPM2CYP3A4
SCHEMBL25974819 1.00 ADK (0.39) ADKFGFR1POLRMTTRPM2CYP3A4
SCHEMBL25969926 1.00 ADK (0.39) ADKFGFR1POLRMTTRPM2CYP3A4
SCHEMBL24407327 1.00 ADK (0.39) ADKFGFR1POLRMTTRPM2CYP3A4
SCHEMBL25974922 1.00 ADK (0.39) ADKFGFR1POLRMTTRPM2CYP3A4
SCHEMBL25969369 1.00 ADK (0.39) ADKFGFR1POLRMTTRPM2CYP3A4
SCHEMBL25975255 1.00 ADK (0.39) ADKFGFR1POLRMTTRPM2CYP3A4
SCHEMBL25971387 0.99 ADK (0.40) ADKFGFR1POLRMTTRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 — — US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 — — US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 ADK 1238/4885FGFR1 4843/4885POLRMT 371/4885
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 ADK 1238/4885FGFR1 4843/4885POLRMT 371/4885
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 ADK 1238/4885FGFR1 4843/4885POLRMT 371/4885
US-11773122-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 ADK 1238/4885FGFR1 4843/4885POLRMT 371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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