Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19534273 | 0.82 | NEK2 (0.42) | CYP11B1CYP11B2SMN1; SMN2NEK2TOP2A | |
| SCHEMBL21673246 | 0.79 | SMN1; SMN2 (0.43) | CYP11B1CYP11B2CRBNSMN1; SMN2OPRM1 | |
| SCHEMBL16190024 | 0.78 | — | — | |
| SCHEMBL1133336 | 0.74 | NEK2 (0.39) | CRBNSMN1; SMN2OPRM1OPRL1NEK2 | |
| SCHEMBL31580458 | 0.74 | OPRM1 (0.42) | CYP11B1CYP11B2CRBNSMN1; SMN2OPRM1 | |
| SCHEMBL6560160 | 0.74 | OR51E2 (0.39) | CRBNSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL16565923 | 0.73 | CYP11B1 (0.46) | CYP11B1CYP11B2SMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL20758273 | 0.72 | SMN1; SMN2 (0.35) | CRBNSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL20633689 | 0.72 | OR51E2 (0.37) | CRBNSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL15987052 | 0.72 | CRBN (0.37) | CRBNSMN1; SMN2OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4310084-A1 | PYRIDOPYRIMIDINE-BASED COMPOUND AND APPLICATION THEREOF | Jinan University (CN) | 2024-01-24 | — | — | EP | disclosed |
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |