SCHEMBL25975705

SCHEMBL25975705

c1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4cc(-c5nc(-c6ccccc6)nc(-c6cccc7oc8ccccc8c67)n5)c5c(c4)oc4ccccc45)cc3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.33
MAPT P10636 4/20 0.33
POLB P06746 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ALOX15 P16050 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 3/20 0.32
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
CRHR1 P34998 1/20 0.32
HPGD P15428 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24255391 0.97 MAPT (0.35) TSHRMAPTPOLBLMNAHTT
SCHEMBL24255397 0.97 MAPT (0.35) TSHRMAPTPOLBLMNAHTT
SCHEMBL26415417 0.97 MAPT (0.35) TSHRMAPTPOLBLMNAHTT
SCHEMBL24255399 0.95 MAPT (0.35) TSHRMAPTPOLBLMNAHTT
SCHEMBL26415458 0.95 ALDH1A1 (0.38) TSHRMAPTPOLBLMNAHTT
SCHEMBL22112545 0.94 PLA2G2A (0.33) TSHRMAPTPOLBLMNAHTT
SCHEMBL26571720 0.94 ALDH1A1 (0.37) TSHRMAPTPOLBLMNAHTT
SCHEMBL24066080 0.93 TSHR (0.33) TSHRMAPTPOLBLMNAHTT
SCHEMBL25975513 0.92 HCRTR1 (0.35) TSHRMAPTPOLBLMNAHTT
SCHEMBL25975703 0.92 ALDH1A1 (0.36) TSHRMAPTPOLBLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149718-A1 ORGANIC LIGHT-EMITTING ELEMENT INCLUDING HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING ELEMENT, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING ELEMENT 엘티소재주식회사 2023-08-10 WO disclosed