SCHEMBL25975709

SCHEMBL25975709

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4cc(-c5cc(N(c6ccccc6)c6ccc7ccccc7c6)cc6oc7ccccc7c56)ccc4c3)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP1A2 P05177 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 4/20 0.32
NR1H4 Q96RI1 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
CCR4 P51679 1/20 0.31
POLB P06746 2/20 0.31
TERT O14746 1/20 0.30
TSHR P16473 3/20 0.30
HPGD P15428 2/20 0.30
ALOX15 P16050 1/20 0.30
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25975707 0.95 ALDH1A1 (0.33) KDM4EALDH1A1HSD17B10CYP1A2KMT2A
SCHEMBL26415469 0.95 KDM4E (0.38) KDM4EALDH1A1HSD17B10CYP1A2KMT2A
SCHEMBL25666438 0.94 MAPT (0.33) KDM4EALDH1A1HSD17B10CYP1A2KMT2A
SCHEMBL24899569 0.93 KDM4E (0.34) KDM4EALDH1A1HSD17B10CYP1A2KMT2A
SCHEMBL24066124 0.93 KDM4E (0.36) KDM4EALDH1A1HSD17B10CYP1A2KMT2A
SCHEMBL24899587 0.91 ALDH1A1 (0.33) KDM4EALDH1A1HSD17B10CYP1A2KMT2A
SCHEMBL24255422 0.91 KDM4E (0.36) KDM4EALDH1A1HSD17B10CYP1A2KMT2A
SCHEMBL26415521 0.91 KDM4E (0.34) KDM4EALDH1A1HSD17B10CYP1A2KMT2A
SCHEMBL25975777 0.89 CYP1A1 (0.36) KDM4EALDH1A1HSD17B10CYP1A2KMT2A
SCHEMBL26415457 0.89 PLA2G2A (0.34) KDM4EALDH1A1CYP1A2KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149718-A1 ORGANIC LIGHT-EMITTING ELEMENT INCLUDING HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING ELEMENT, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING ELEMENT 엘티소재주식회사 2023-08-10 WO disclosed