Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 12/20 | 0.55 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17306996 | 0.83 | CARM1 (0.55) | CARM1PRMT5WDR77HTTLMNA | |
| SCHEMBL15830399 | 0.83 | CARM1 (0.55) | CARM1PRMT5WDR77 | |
| SCHEMBL3418321 | 0.81 | CARM1 (0.60) | CARM1PRMT5WDR77HTTLMNA | |
| SCHEMBL30019323 | 0.81 | CARM1 (0.74) | CARM1PRMT5WDR77HTTLMNA | |
| SCHEMBL5451149 | 0.80 | LMNA (0.61) | CARM1PRMT5WDR77HTTKDM4E | |
| SCHEMBL25910580 | 0.80 | CARM1 (0.71) | CARM1PRMT5WDR77HTTKDM4E | |
| SCHEMBL20042490 | 0.80 | CARM1 (0.71) | CARM1PRMT5WDR77HTTKDM4E | |
| SCHEMBL13875133 | 0.80 | CARM1 (0.71) | CARM1PRMT5WDR77HTTKDM4E | |
| SCHEMBL25059799 | 0.79 | CARM1 (0.57) | CARM1PRMT5WDR77HTTLMNA | |
| SCHEMBL22527575 | 0.79 | CARM1 (0.61) | CARM1PRMT5WDR77HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |