Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.56 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848463 | 0.83 | LMNA (0.46) | LMNAHTTPRMT5WDR77CARM1 | |
| SCHEMBL3418321 | 0.80 | CARM1 (0.60) | LMNAHTTPRMT5WDR77CARM1 | |
| SCHEMBL30019323 | 0.80 | CARM1 (0.74) | LMNAHTTPRMT5WDR77CARM1 | |
| SCHEMBL5455348 | 0.80 | LMNA (0.46) | LMNAHTTPRMT5WDR77CARM1 | |
| SCHEMBL13039124 | 0.79 | CARM1 (0.52) | LMNAHTTPRMT5WDR77CARM1 | |
| SCHEMBL12573430 | 0.78 | CARM1 (0.51) | LMNAHTTPRMT5WDR77CARM1 | |
| SCHEMBL25059799 | 0.77 | CARM1 (0.57) | LMNAHTTPRMT5WDR77CARM1 | |
| SCHEMBL22527575 | 0.77 | CARM1 (0.61) | LMNAHTTPRMT5WDR77CARM1 | |
| SCHEMBL15823950 | 0.77 | CARM1 (0.61) | LMNAHTTPRMT5WDR77CARM1 | |
| SCHEMBL18212446 | 0.77 | CARM1 (0.57) | LMNAHTTPRMT5WDR77CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | IONIX PHARMACEUTICALS LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | SCN1B, SCN1A, SCN10A | LMNA 1282/4885HTT 1961/4885PRMT5 3172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.