Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25976421 | 0.85 | PSMB5 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25668395 | 0.83 | FAAH (0.44) | NPC1RAB9AKMT2AMEN1MMP2 | |
| SCHEMBL25976092 | 0.82 | NPC1 (0.42) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24982400 | 0.79 | SMN1; SMN2 (0.47) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25975656 | 0.79 | NPC1 (0.51) | NPC1RAB9ASIGMAR1KMT2AMEN1 | |
| SCHEMBL24183747 | 0.78 | SMN1; SMN2 (0.64) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24642659 | 0.78 | NPC1 (0.59) | NPC1RAB9ASIGMAR1KMT2AMEN1 | |
| SCHEMBL10136058 | 0.76 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL19293154 | 0.76 | NPC1 (0.58) | NPC1RAB9ASIGMAR1KMT2AMEN1 | |
| SCHEMBL27710873 | 0.76 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223318-A1 | ANTITUMOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |